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Open Access Editorial

Open new possibilities in Transplantation Research

Edward K Geissler1* and Alan Jardine2

Author Affiliations

1 Department of Surgery, University Hospital Regensburg, Regensburg, Germany

2 Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK

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Transplantation Research 2012, 1:1  doi:10.1186/2047-1440-1-1

Published: 24 April 2012

First paragraph (this article has no abstract)

The field of organ, tissue and cell transplantation through the recent decades has revolutionised treatment options for some of the most critically ill patients. Advancements in this discipline have been dramatic and provided life saving options, with a good quality of life, for patients with previously untreatable conditions. Both researchers and the public remain fascinated with the concept of transplantation because replacing body parts still seems to be part of science fiction, but yet is somehow possible through extraordinary pioneering research that has become part of routine modern medicine. Nonetheless, many serious issues remain unsolved limiting the further advancement of transplantation medicine, including the severe shortage of available organs/tissues and our inability to prevent immunological rejection without life-long suppression of general immunity with drugs that have substantial side-effects. Indeed, it could be said that the field of transplantation is presently resting uncomfortably on a plateau that most clinicians and researchers feel is far from where we would like to be [1]. Striving for adequate organ availability and preserving long term graft function are principal goals for the coming decades. This will require intensive and innovative basic and clinical research.